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Food allergy mediated by IgG antibodies associated with migraine in adults
Carlos M Arroyave Hernández1, Mauro Echavarría Pinto, Mauro Echevarría Pinto
1Centro de Inmunología y Alergias, Querétaro, Querétaro, México.
Background:
Migraine occurs with a high prevalence of 18 per cent. Management requires a tailored regimen of pharmacological and other measures based on individual clinical history. In some patients, allergen-specific IgG has been suspected to be involved in their mechanism, however, serological methods to investigate such possibility, are seldomly used.
Objective:
The aim of this study was to investigate allergen-specific IgG in serum of patients with migraine refractory to traditional treatment.
Material And Methods:
Serum antibodies to specific 108 food allergens were measured by enzyme immunoassay from 56 patients with migraine and a control group without migraine.
Results:
In addition to statistical significant differences in the number of positives for IgG food allergens between patients with migraine and a controlled group, elimination diets successfully control the migraine without the need of medications.
Conclusion:
According to the results obtained, serum IgG antibodies to common food should be investigated in patients with migraine.
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