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A peptide-based, ratiometric biosensor construct for direct fluorescence detection of a protein analyte

Karin Enander1, Laurence Choulier, A Linnéa Olsson

  • 1Division of Molecular Physics, Department of Physics, Chemistry and Biology, Linkoping University, 58183 Linkoping, Sweden. karen@ifm.liu.se

Bioconjugate Chemistry
|August 13, 2008
PubMed
Summary

We developed novel peptide-based fluorescent biosensors for protein detection. These constructs enable reagentless quantification by monitoring changes in fluorescence intensity ratios upon analyte binding.

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