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Updated: Jul 2, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
Published on: September 14, 2018
The role of IL-10 in preventing food-induced anaphylaxis
Christophe P Frossard1, Philippe A Eigenmann
1Department of Paediatrics, University Hospital of Geneva, 6 rue Willy-Donze, 1211 Geneva 14, Switzerland.
Background:
Food allergy is a common condition resulting in a much impaired quality of life. So far, no clearly effective preventive and therapeutic strategies have been established. However, several options have been tested with promising results.
Objective:
This review examines the potential of various strategies involving an IL-10-mediated effect for tolerance induction to food antigens, mostly for preventing food allergy.
Methods:
In addition to a review of the literature, we describe and comment on experiments involving a Lactoccocus lactis strain transfected to secrete murine IL-10 directly into the gut.
Results/Conclusion:
This strain was efficient at preventing subsequent sensitization with a common food allergen. There appears to be a potential for such strategies for the prevention of human food allergy but further investigations will be needed to explore them.
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