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Gene therapy of arthritis and orthopaedic disorders: current experimental approaches in China and in Canada
Ke-Rong Dai1, Xiao-Ling Zhang, Qin Shi
1Shanghai Jiao Tong University, Insititue of Health Sciences, School of Medicine, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, China.
Background:
Gene therapy offers new possibilities for the clinical management of orthopaedic conditions that are difficult to treat by traditional surgical or medical means.
Objective:
This review discusses the different gene therapy strategies available today, the safety issues with which they may be associated, and the potential for cooperation between China and Canada.
Results/Conclusion:
In the last decade, extensive improvements have been made to optimize gene therapy and have been tested on several orthopaedic conditions. China is a pioneer in some fields of gene therapy; the first anticancer gene therapy drug has been licensed in China. Canada has a very active research establishment and a populace that embraces new scientific developments, especially in medical sciences.
