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In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Ventriculitis due to Staphylococcus lugdunensis: two case reports
Teresa Spanu1, Donato Rigante, Gianpiero Tamburrini
1Institute of Microbiology, Catholic University of the Sacred Heart, Rome, Italy. tspanu@rm.unicatt.it
Introduction:
Staphylococcus lugdunensis is an unusually virulent coagulase-negative staphylococcus that has rarely been implicated in central nervous system infections.
Case Presentation:
Two children hospitalized in the Neurosurgery Unit developed ventriculitis caused by methicillin-resistant Staphylococcus lugdunensis following placement of external ventriculostomy drains. The causative organisms were identified by molecular studies. The patients recovered without significant sequelae after high doses of intrathecal vancomycin.
Conclusion:
Distinguishing Staphylococcus lugdunensis from other coagulase-negative staphylococcus species is crucial because it carries a substantial risk for severe central nervous system infections displayed by patients with implanted cerebrospinal fluid devices. Clinicians should not underestimate the importance of the isolation of this species from cerebrospinal fluid specimens.
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