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Updated: Jul 2, 2026
07:21
Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Giant intracranial aneurysms: endovascular challenges
Richard J Parkinson1, Christopher S Eddleman, H Hunt Batjer
1Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.
Neurosurgery
|August 22, 2008
Summary
Treating giant aneurysms is challenging. While endovascular coiling alone is disappointing, new stent and coil technologies offer promising reconstructive approaches for parent vessel repair, improving outcomes.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Vascular Surgery
Background:
- Giant aneurysms present significant treatment challenges for both surgical and endovascular methods.
- Traditional endovascular coiling as a primary therapy for giant aneurysms has yielded suboptimal results.
Purpose of the Study:
- To review endovascular treatment strategies for giant aneurysms published after 1994.
- To evaluate the efficacy and outcomes of deconstructive and reconstructive endovascular techniques.
Main Methods:
- Literature review of endovascular treatment strategies for giant aneurysms.
- Analysis of studies published after the FDA approval of Guglielmi detachable coils.
- Review of follow-up, durability, and occlusion rates where available.
Main Results:
- Endovascular coiling as a primary treatment for giant aneurysms has shown disappointing occlusion rates.
- Hunterian strategies have demonstrated more success in published series.
- Recent advancements in coil, glue, and stent technology show potential for parent vessel reconstruction.
Conclusions:
- Parent vessel reconstruction using advanced endovascular techniques offers a promising approach for giant aneurysms.
- New technologies may allow for acceptable morbidity, mortality, and long-term durability.
- Further research into reconstructive endovascular strategies is warranted.
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