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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Current concepts in the management of intracranial atherosclerotic disease

Robert D Ecker1, Elad I Levy, Eric Sauvageau

  • 1Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.

Neurosurgery
|August 22, 2008
PubMed

Insights

Patients with symptomatic intracranial atherosclerosis face a high stroke risk. Advances in endovascular treatments offer new hope for managing this condition.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Interventional Neuroradiology

Background:

  • Medically refractory symptomatic intracranial atherosclerotic disease carries a poor prognosis.
  • The Warfarin-Aspirin Symptomatic Intracranial Disease study indicated a 13-14% risk of ipsilateral stroke at 1.8 years for these patients.

Purpose of the Study:

  • To discuss recent clinical developments and concepts in the diagnosis and endovascular treatment of intracranial atherosclerotic disease.

Main Methods:

  • Review of synergistic advances in intracranial angioplasty and stenting.
  • Integration of modern neuroimaging techniques.
  • Evaluation of periprocedural and postprocedural antithrombotic regimens.

Main Results:

  • Emerging models for diagnosis and successful endovascular treatment of intracranial stenosis.
  • Improved understanding of risk factors and outcomes in intracranial atherosclerosis.

Conclusions:

  • Synergistic advances are creating new paradigms for managing intracranial atherosclerotic disease.
  • Endovascular approaches combined with advanced imaging and antithrombotic strategies offer improved outcomes.

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