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[Two cases of radiation-induced sarcoma after radiation therapy in nasopharyngeal carcinoma]
Akira Okoshi1, Kiyoto Shiga, Kazuha Sasaki
1Department of Otolaryngology-Head & Neck Surgery, Tohoku University Hospital, Sendai.
Nihon Jibiinkoka Gakkai Kaiho
|August 14, 2008
Abstract:
We report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma. Case 1: A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2: A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease.
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