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Aeromonas-associated diarrhoea in north India
S Ram1, S Khurana, S B Khurana
1Department of Microbiology and Medicine, Dayanand Medical College and Hospital, Ludhiana, India.
Journal of Diarrhoeal Diseases Research
|March 1, 1991
Summary
Aeromonas bacteria caused diarrhoea in 2.1% of patients in India. Most Aeromonas isolates were enterotoxigenic and susceptible to common antibiotics, except ampicillin and cephalothin.
Area of Science:
- Microbiology
- Infectious Diseases
- Gastroenterology
Background:
- Aeromonas species are recognized as potential enteropathogens.
- Diarrhoeal diseases remain a significant public health concern globally.
- Understanding the prevalence and characteristics of Aeromonas infections is crucial for effective management.
Purpose of the Study:
- To investigate the incidence of Aeromonas-associated diarrhoea in patients in Ludhiana, India.
- To identify Aeromonas species and assess their enterotoxigenicity.
- To determine the antimicrobial susceptibility patterns of isolated Aeromonas strains.
Main Methods:
- Microbiological examination of faecal samples from 2,661 patients and 105 healthy controls.
- Isolation and identification of Aeromonas species.
- Enterotoxigenicity testing using the rabbit ileal loop assay.
- Antimicrobial susceptibility testing against common agents.
Main Results:
- Aeromonas species were isolated from 2.1% of patients (55/2661).
- Enterotoxigenic strains included 7/25 A. caviae, all 18 A. sobria, and all 7 A. hydrophila isolates.
- No cross-reactivity was observed between Aeromonas enterotoxin and E. coli labile toxin.
- Most isolates were susceptible to common antimicrobial agents, but resistant to ampicillin and cephalothin.
Conclusions:
- Aeromonas species are an infrequent cause of diarrhoea in the studied population.
- Enterotoxigenic potential exists within A. caviae, A. sobria, and A. hydrophila.
- Antimicrobial resistance patterns highlight the need for judicious antibiotic selection in treating Aeromonas infections.