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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
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Self-assembled monolayers derived from a double-chained monothiol having chemically dissimilar chains.

Shishan Zhang1, Andrew C Jamison, Daniel K Schwartz

  • 1Departments of Chemistry and Chemical Engineering, University of Houston, Houston, TX 77204-5003, USA.

Langmuir : the ACS Journal of Surfaces and Colloids
|August 14, 2008
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Self-assembled monolayers (SAMs) from a double-chained fluorinated thiol show less ordered alkyl chains and more tilted fluorocarbons compared to single-chained thiols. Despite this, homogeneous monolayer films are formed on gold surfaces.

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Area of Science:

  • Surface Chemistry
  • Materials Science
  • Nanotechnology

Background:

  • Self-assembled monolayers (SAMs) are crucial for modifying surface properties.
  • Fluorinated thiols offer unique characteristics for surface engineering.
  • Understanding the structure-property relationships of SAMs is vital for advanced applications.

Purpose of the Study:

  • To investigate the structure and conformation of SAMs formed by a novel double-chained partially fluorinated thiol on gold.
  • To compare the properties of these SAMs with those derived from single-chained thiols (both normal and fluorinated).
  • To elucidate the impact of double-chained adsorbates on monolayer packing, ordering, and orientation.

Main Methods:

  • Ellipsometry for thickness and refractive index measurements.
  • Contact angle goniometry to assess surface wettability and homogeneity.
  • Polarization Modulation Infrared Reflection-Absorption Spectroscopy (PM-IRRAS) for conformational analysis.
  • X-ray Photoelectron Spectroscopy (XPS) for elemental composition and chemical states.

Main Results:

  • The double-chained fluorinated thiol forms SAMs with less densely packed and less conformationally ordered alkyl chains compared to single-chained analogues.
  • The fluorocarbon moieties in the double-chained SAMs exhibit a greater tilt angle from the surface normal than in single-chained fluorinated SAMs.
  • Low contact angle hysteresis indicates the formation of homogeneous monolayer films by the double-chained thiol.

Conclusions:

  • Double-chained fluorinated thiols yield SAMs with distinct structural characteristics, including reduced chain packing and increased tilt of fluorinated segments.
  • Despite structural differences, these double-chained thiols can form homogeneous monolayers on gold surfaces.
  • The findings provide insights into designing functionalized surfaces with tailored properties using complex thiol adsorbates.