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Related Concept Videos

Ion Channels01:19

Ion Channels

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow specific...
Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle01:19

Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle

Inductively coupled plasma (ICP) is the most widely used plasma source in atomic emission spectroscopy (AES), also known as Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The ICP source, or torch, consists of three concentric quartz tubes with argon gas flowing through them. A spark from a Tesla coil initiates the ionization of argon, generating a high-temperature plasma.
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
Chemical Ionization (CI) Mass Spectrometry01:21

Chemical Ionization (CI) Mass Spectrometry

The molecular ion peak of a molecule in the mass spectrum provides vital information for molecular identification. However, conventional electron impact ionization can lead to the rapid dissociation of some molecular ions before they reach the detector. A milder ionization method is required to increase the lifetime of such ionized analyte molecules. Chemical ionization (CI) is a gas-phase protonation reaction useful for mass-analyzing analyte molecules that are easily protonated to yield the...
Facilitated Transport01:19

Facilitated Transport

The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a membrane via...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...

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Updated: Jul 2, 2026

Controllable Ion Channel Expression through Inducible Transient Transfection
10:00

Controllable Ion Channel Expression through Inducible Transient Transfection

Published on: February 17, 2017

Self-triggered channel ion source.

C Bouchard1, J D Carette

  • 1Centre de Recherches sur les Atomes et les Molecules (CRAM), Faculte des Sciences et de Genie, Universite Laval, Ste-Foy, P. Quebec, Canada, G1K 7P4.

The Review of Scientific Instruments
|January 1, 1979
PubMed
Summary
This summary is machine-generated.

A novel ion source utilizes a continuous dynode electron multiplier for enhanced ion current intensity. This advancement significantly boosts performance for applications in gaseous mass spectrometry.

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Last Updated: Jul 2, 2026

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Published on: February 17, 2017

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
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Area of Science:

  • Physics and Analytical Chemistry
  • Instrument Development

Background:

  • Traditional ion sources often have limitations in ion current intensity.
  • Continuous dynode electron multipliers offer potential for signal amplification.

Purpose of the Study:

  • To describe a new ion source design based on a straight channel continuous dynode electron multiplier and an ion reflector.
  • To present the operating characteristics and ion analysis of the developed ion source.
  • To demonstrate the enhanced ion current intensity compared to existing devices.

Main Methods:

  • Construction of an ion source utilizing a straight channel continuous dynode electron multiplier.
  • Integration of an ion reflector device with the multiplier.
  • Characterization of operating parameters and analysis of produced ions.

Main Results:

  • The ion source operates on a principle of a self-sustained ion and electron cascade.
  • The total ion current intensity achieved is in the range of 10(-9) to 10(-8) A.
  • The ion current is enhanced by at least six orders of magnitude compared to similar prior devices.

Conclusions:

  • The developed ion source demonstrates significantly enhanced ion current intensity.
  • The device is suitable for applications in gaseous mass spectrometry.
  • The principle of operation offers a robust method for ion generation and amplification.