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Bioreactor Controls-I01:28

Bioreactor Controls-I

Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly monitored using...
Pressure Gauges01:20

Pressure Gauges

Most pressure gauges, like those on scuba tanks, are calibrated to read zero at atmospheric pressure. Readings from such gauges are called the gauge pressure, which is the pressure relative to atmospheric pressure. When the pressure inside the tank exceeds atmospheric pressure, the gauge reports a positive value. Some gauges are designed to measure negative pressure. For example, many physics experiments must take place in a vacuum chamber, a rigid chamber from which some of the air is pumped...
Pressure of Fluids01:14

Pressure of Fluids

There are many examples of pressure in fluids in everyday life, such as in relation to blood (high or low blood pressure) and in relation to weather (high- and low-pressure weather systems). A given force can have a significantly different effect, depending on the area over which the force is exerted. For instance, a force applied to an area of 1 mm2 has a pressure that is 100 times greater than the same force applied to an area of 1 cm2. That's why a sharp needle is able to poke through skin...
Fluid Pressure01:14

Fluid Pressure

In mechanical engineering, fluid pressure plays a critical role in designing systems that utilize liquid flow, such as hydraulic systems, pumps, and valves. When designing these systems, engineers must ensure they can withstand the forces created by fluid pressure to avoid damage or failure.
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Fluid Pressure over Curved Plate of Constant Width01:12

Fluid Pressure over Curved Plate of Constant Width

When a curved plate of constant width is submerged in a liquid, the pressure acting normal to the plate varies continuously both in magnitude and direction. Calculating the magnitude and location of the resultant force at a point is often challenging for such cases. One of the methods to determine the resultant force and its location involves separately calculating the horizontal and vertical components of the resultant force. This complex calculation can be simplified by representing the...
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Concept of Pressure at a Point

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Related Experiment Video

Updated: Jul 2, 2026

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
07:12

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves

Published on: August 23, 2011

Cell design for pressure to 25 kbar.

J E Schoutens1, S S Senesac

  • 1General Electric Company--TEMPO, Center for Advanced Studies, Santa Barbara, California 93102, USA.

The Review of Scientific Instruments
|November 1, 1979
PubMed
Summary
This summary is machine-generated.

This study introduces a novel cell design for high-pressure experiments up to 25 kbar using candle wax as a pressure medium. The design ensures no detectable leakage and accurately measures internal pressure for reliable material studies.

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Last Updated: Jul 2, 2026

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Area of Science:

  • Materials Science
  • High-Pressure Physics
  • Experimental Design

Background:

  • High-pressure experiments are crucial for understanding material properties under extreme conditions.
  • Existing cell designs face challenges in sealing and accurate pressure measurement at high hydrostatic pressures.

Purpose of the Study:

  • To present a novel cell design for hydrostatic pressure experiments up to 25 kilobar (kbar).
  • To ensure reliable pressure transmission and accurate internal pressure measurement in high-pressure environments.

Main Methods:

  • Utilized candle wax as the pressure-transmitting medium.
  • Employed molybdenum disulfide impregnated nylon and aluminum disks for sealing.
  • Developed a method to compute internal cavity pressure from applied and transmitted loads, including frictional forces.

Main Results:

  • The cell design demonstrated no detectable leakage up to 25 kbar.
  • Internal pressure measurements were within 9% of phase-transition data for RbCl and KBr between 3-25 kbar.
  • The method provides accurate pressure calibration for high-pressure research.

Conclusions:

  • The presented cell design is effective and reliable for hydrostatic pressure experiments up to 25 kbar.
  • The sealing method and pressure computation technique ensure data integrity in extreme conditions.
  • This design facilitates advanced research in condensed matter physics and materials science.