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Updated: Jul 2, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Update on the diagnosis and management of prostate cancer
1Department of Urology, State University of New York, Upstate Medical University, 750 East Adams Street, Syracuse, NY 31210, USA.
Abstract:
Early detection of prostate adenocarcinoma (prostate cancer) through screening tests such as a serum prostate-specific antigen (PSA) test and a digital rectal examination (DRE) enables primary care physicians and urologists to offer patients a broader choice of treatments that are also more likely to provide a cure. Whether men are being over treated or over diagnosed through the widespread use of screening tests remains controversial. This review aims to provide general practitioners with a better understanding of different prostate cancer tests that can be performed and to help them decide which patients should be referred to a urologist for an ultrasound-guided biopsy.
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