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Updated: Jul 2, 2026

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
[Metabolic syndrome and mild hypertension]
12nd Department of Internal Medicine, Sapporo Medical University.
Abstract:
The clinical definition of Metabolic Syndrome in Japan was issued in April, 2005 by a committee which is consisted of related 8 Japanese societies. The Japanese definition indicates that both abdominal obesity(AO male > or = 85 cm, female > or = 90cm) as a required component, and two out of three following factors, high blood pressure(BP > or = 130/ > or = 85mmHg), dyslipidemia(high triglyceride: TG > or = 150 mg/dL and/or low HDL-cholesterol : HDL-C < 40 mg/dL), and high fasting plasma glucose (FPG > or = 110 mg/dL) are necessary for the diagnosis. This concept is mostly the same with IDF. The blood pressure criteria of Japanese definition is over 130/85 mmHg. Frequency of high normal blood pressure and mild hypertension were 21.5% and 30.0% in male and 18.4% and 24.2% in female over 40 years old, respectively. High blood pressure was most frequent risk factor among metabolic syndrome components. The control of high normal or mild hypertension is very important to prevent the cardiovascular risk in metabolic syndrome.
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