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Aggressive angiomyxoma in men.

M S Hastak1, S R Raghuvanshi, Shilpi Sahu

  • 1Department of Pathology, Grant Medical College, Mumbai 400 008.

The Journal of the Association of Physicians of India
|August 15, 2008
PubMed
Summary
This summary is machine-generated.

Aggressive angiomyxoma is a rare tumor typically found in women. This report details a case in a 65-year-old male, highlighting its unusual occurrence in male urologic pathology.

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Area of Science:

  • Urologic Pathology
  • Surgical Oncology

Background:

  • Aggressive angiomyxoma (AA) is a rare mesenchymal neoplasm.
  • It predominantly affects the pelvic and perineal regions of reproductive-aged females.
  • Recognition in male urologic pathology is limited.

Observation:

  • A 65-year-old male presented with a 2-year history of a progressively enlarging left perineal mass.
  • CT imaging revealed a well-defined, lobulated mass in the left ischiorectal fossa.
  • The mass extended into the subcutaneous plane.

Findings:

  • Microscopic examination showed stellate to spindle-shaped cells within a loose myxoid stroma.
  • Numerous thin- to thick-walled blood vessels were present.
  • Key features of malignancy, such as pleomorphism, hyperchromatism, and mitotic activity, were absent.

Implications:

  • This case underscores the importance of considering aggressive angiomyxoma in the differential diagnosis of perineal masses in males.
  • Despite its rarity in men, AA is a benign tumor.
  • Wide excisional surgery is the recommended treatment approach.