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Coronary slow flow: description of a new "cardiac Y" syndrome

Massimo Fineschi, Tommaso Gori

    International Journal of Cardiology
    |August 15, 2008
    PubMed

    Insights

    Unexplained chest pain (angina) with normal arteries can stem from coronary slow flow, a condition with high resting vascular resistance. This novel syndrome, termed coronary syndrome Y, causes unstable angina and differs from coronary syndrome X.

    Area of Science:

    • Cardiology
    • Vascular Physiology
    • Clinical Medicine

    Background:

    • Angina with unobstructed coronary arteries is a common clinical problem.
    • Impaired coronary flow reserve, affecting the ability to adjust blood flow during exercise, can cause ischemia and angina.

    Observation:

    • A case of coronary slow flow is presented, characterized by inappropriately high resting microvascular resistances.
    • This condition led to unstable angina in the described patient.

    Findings:

    • Coronary slow flow represents a distinct pathophysiological entity.
    • The proposed term 'coronary syndrome Y' differentiates this condition from the established 'coronary syndrome X'.

    Implications:

    • Recognizing coronary syndrome Y is crucial for diagnosing and managing patients with angina and normal coronary arteries.
    • This distinction may improve diagnostic accuracy and therapeutic strategies for this patient group.

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