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Highly functionalized 7-azaindoles as selective PPAR gamma modulators

Sheryl D Debenham1, Audrey Chan, Fiona Waiyu Lau

  • 1Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA.

Bioorganic & Medicinal Chemistry Letters
|August 15, 2008
PubMed
Summary

New 7-azaindole compounds are potent selective PPARgamma modulators (SPPARgammaMs). Modifications improved their effectiveness and how the body processes them, with better safety profiles than older compounds.

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