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Updated: Jul 2, 2026
07:02
Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Kaposi's sarcoma in a patient with AIDS.
M M Kura1, U N Khemani, D N Lanjewar
1Department of Dermatology and Veneorology, Grant Medical College and Sir J. J. Hospital, Mumbai.
The Journal of the Association of Physicians of India
|August 16, 2008
Summary
A rare case of Kaposi
Area of Science:
- Oncology
- Infectious Diseases
- Dermatology
Background:
- Kaposi's sarcoma (KS) is an AIDS-defining malignancy.
- Human herpesvirus 8 (HHV-8) is the causative agent.
- KS is endemic in certain regions but rare in others.
Observation:
- A 40-year-old Somali male, diagnosed with HIV, presented with characteristic skin lesions.
- Lesions included painful, livid reddish-brown plaques, papules, and nodules on the lower limbs.
- Purplish-red nodules were also observed on the hard palate.
Findings:
- Biopsy of the cutaneous nodular lesions confirmed the diagnosis of Kaposi's sarcoma.
- The presentation highlights a rare occurrence of KS in the Indian subcontinent's literature.
Implications:
- This case underscores the importance of recognizing KS in HIV-positive individuals, even in low-prevalence regions.
- Increased awareness and diagnostic vigilance for KS are crucial in diverse geographical settings.
- Further research into the epidemiology and presentation of KS in underreported areas is warranted.
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