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Updated: Jul 2, 2026

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion
Published on: May 4, 2011
Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli
Felix Bermpohl1, Alvaro Pascual-Leone, Amir Amedi
1Berenson-Allen Center for Non-Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. felix.bermpohl@charite.de
Abstract:
In a functional magnetic resonance imaging experiment, expectancy cues signaling emotional stimuli were used to study the personality trait of novelty seeking. BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability.
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