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Updated: Jul 2, 2026

Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry
Published on: July 31, 2011
Peptide mass fingerprinting using isotopically encoded photo-crosslinking amino acids
Bryan J Wilkins1, Kelly A Daggett, T Ashton Cropp
1Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Abstract:
When isotopically labelled photo-crosslinking amino acids are site-specifically incorporated into proteins, in combination with the corresponding non-labeled analogue, cross-linked tryptic peptides are easily identified in mass spectra via characteristic "doublet" patterns.
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