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Updated: Jul 2, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

Argatroban in short-term percutaneous ventricular assist subsequent to heparin-induced thrombocytopenia

David P Webb1, Matthew T Warhoover, Susan S Eagle

  • 1Vanderbilt Heart Institute, Division of Perfusion Services, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA. david.webb@vanderbilt.edu

The Journal of Extra-Corporeal Technology
|August 19, 2008
PubMed

Heparin-induced thrombocytopenia paradoxically is a transient pro-thrombotic disorder triggered by heparin exposure. If not treated appropriately, it can be life threatening because of its related thromboembolic complications. In particular, it presents a unique challenge in patients needing extracorporeal life support, because anticoagulation is essential for safe management. This case report describes the safe, efficacious use of Argatroban during short-term support of a patient with a percutaneously inserted left ventricular assist TandemHeart device.

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