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Updated: Jul 2, 2026
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Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases
Published on: December 6, 2016
Imaging of cerebral vasculitis
1Department of Neuroradiology, West Wing, The John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK. Wilhelm.Kuker@ndm.ox.ac.uk
Summary
Diagnosing cerebral vasculitis in young patients is challenging. Advanced imaging like magnetic resonance angiography and digital subtraction angiography helps identify vessel narrowing and inflammation in the brain.
Area of Science:
- Neurology
- Radiology
- Vascular Medicine
Background:
- Cerebral vasculitis is a significant cause of ischemic stroke in young individuals.
- Diagnosis can be complex, often requiring advanced imaging techniques.
Purpose of the Study:
- To outline the diagnostic process for cerebral vasculitis.
- To highlight the roles of various imaging modalities in detecting vasculitic stenoses.
Main Methods:
- Initial detection of brain lesions suggestive of vasculitis.
- Utilizing magnetic resonance angiography (MRA) for intracranial stenoses.
- Employing intraarterial digital subtraction angiography (DSA) for medium and small cerebral arteries.
Main Results:
- Multiple infarcts across different vascular territories suggest vasculitis.
- 1.5 T MRA is effective for large artery stenosis.
- DSA remains crucial for evaluating smaller vessel stenoses.
Conclusions:
- Contrast-enhanced MRI can show arterial wall changes in large cerebral vessels.
- Imaging may reduce the need for biopsy in some cases of basal vasculitis.
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