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Published on: July 9, 2020
Management of cervical arterial dissection
1Division of Clinical Neuroscience, St Georges Hospital Medical School, University of London, SW17 0RE, UK. carotid@btopenworld.com
Advances in understanding cervical artery dissection, a common cause of stroke in young people, are paving the way for new medical and surgical treatments. This review summarizes recent progress in the field.
Area of Science:
- Neurology
- Vascular Medicine
- Radiology
Background:
- Recent clinical, pathological, and radiological advances have significantly improved understanding of cervical artery dissection.
- Progress has been made in understanding the incidence and underlying mechanisms of cervical artery dissection.
Purpose of the Study:
- To summarize recent progress in the understanding of cervical artery dissection.
- To highlight implications for future medical and surgical therapies.
Main Methods:
- Review of numerous published studies, primarily from the last decade.
- Synthesis of data on etiology, neuroimaging, arterial pathology, and genetic basis.
Main Results:
- A rapidly evolving database exists, particularly concerning etiology and neuroimaging.
- Recent studies have focused on arterial pathology and its genetic underpinnings.
Conclusions:
- Cervical artery dissection (carotid and vertebral arteries) is a major, often underdiagnosed, cause of stroke, particularly in young individuals.
- Advances in clinical, epidemiological, radiological, and pathological data provide a basis for future therapeutic trials.
- Future interventions may involve both pharmacological and device-based treatments.
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