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Updated: Jul 2, 2026

Assaying β-amyloid Toxicity using a Transgenic C. elegans Model
13:59

Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

Published on: October 9, 2010

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid

Katja Kanninen1, Tarja M Malm, Henna-Kaisa Jyrkkänen

  • 1Department of Neurobiology, AI Virtanen Institute for Molecular Sciences, Kuopio University, Kuopio, Finland.

Molecular and Cellular Neurosciences
|August 19, 2008
PubMed
Summary

The Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is impaired in Alzheimer's disease (AD). Boosting Nrf2 activity protects against amyloid-beta toxicity, suggesting a therapeutic target for AD.

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