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Updated: Jul 2, 2026
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Published on: July 5, 2021
Intracranial tuberculoma with adjacent inflammatory aneurysms
In-Young Kim1, Shin Jung, Tae-Young Jung
1Brain Tumor Clinic and Gamma Knife Center, Department of Neurosurgery, Chonnam National University, Hwasun Hospital, 160 Ilsimri, Hwasun-eup, Hwasun-gun, Chonnam 519-809, Republic of Korea.
Summary
This is the first reported case of intracranial tuberculoma with associated inflammatory aneurysms. The study discusses the potential development mechanism of these co-occurring conditions.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Tuberculosis can present with diverse neurological complications.
- Intracranial tuberculomas are rare but serious manifestations of tuberculosis.
Observation:
- A 28-year-old woman with a history of pulmonary tuberculosis presented with seizures.
- Brain MRI revealed a left parietal lobe lesion consistent with tuberculoma.
- Surgical exploration unexpectedly identified multiple small aneurysms in adjacent middle cerebral arteries.
Findings:
- The resected lesion was confirmed as a tuberculoma.
- The aneurysms were deemed inflammatory and likely associated with the tuberculosis.
- Surgical management included mass removal and aneurysm repair.
Implications:
- This case highlights a novel association between intracranial tuberculoma and inflammatory aneurysms.
- Understanding the pathogenesis of these co-occurring conditions is crucial for diagnosis and treatment.
- Further research may elucidate the inflammatory mechanisms linking tuberculosis to cerebral aneurysm formation.
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