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Updated: Jul 2, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Pemphigus and infectious agents.

Lior Sagi¹, Yaniv Sherer, Henri Trau

¹Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel.

Autoimmunity Reviews

|August 19, 2008

Summary

This summary is machine-generated.

Pemphigus, an autoimmune skin disease, involves blistering due to genetic and environmental factors. This review explores the link between pemphigus and preceding or worsening viral and bacterial infections.

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Granulocyte-dependent Autoantibody-induced Skin Blistering

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Published on: October 12, 2012

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

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Published on: June 17, 2025

Area of Science:

Dermatology
Immunology
Infectious Diseases

Background:

Pemphigus is a group of autoimmune blistering diseases.
It involves epidermal cell adhesion loss, leading to skin and mucosal blisters.
Disease development is linked to genetic predisposition and environmental triggers.

Purpose of the Study:

To review existing literature on the relationship between pemphigus and infectious agents.
To investigate the role of viral and bacterial pathogens in pemphigus onset or exacerbation.

Main Methods:

Literature review of scientific articles.
Analysis of studies reporting on pemphigus and infectious agents.
Synthesis of findings on viral and bacterial involvement.

Main Results:

Infectious agents, including viruses and bacteria, have been identified as potential triggers or exacerbating factors in pemphigus.
Evidence suggests a connection between specific pathogens and the development or worsening of pemphigus.

Conclusions:

Infectious agents are significant environmental factors implicated in pemphigus pathogenesis.
Further research is warranted to elucidate the precise mechanisms linking infections to pemphigus.