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Evolution of cell interactions with extracellular matrix during carcinogenesis

A Y Alexandrova1

  • 1Institute of Carcinogenesis, Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia. tonya_alex@yahoo.com.

Biochemistry. Biokhimiia
|August 19, 2008
PubMed
Summary

Cellular interactions with the extracellular matrix (ECM) are crucial for cell migration and spread, especially in tumor progression. Understanding these cell-matrix adhesions offers new therapeutic targets for inhibiting cancer invasion and metastasis.

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