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Updated: Jul 2, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
[Life events in correlation with the intensity and entity of depressive disorder]
Abstract:
The article deals with types of life events preceding the onset or repeated episodes of endogenous (major) depression, as well as their influence on the intensity of depressive symptoms in hospitalized patients. It was found that events with intensive long-term contextual threat more often precede the first episode than the repeated depressive episodes (4 cases), although the difference was not statistically significante (F=0.12 F>0.05). Loss (death or separation from a close person) is an event. Recent in closeds relation with the onset of depressive disorder and far more often procedes the first than the repeated (1 case) episode. The difference was statistically significant (F=0.018 P<0.05). It seems that, due to the exhaustion of defensive mechanisms, a mild stress is sufficient to provoke a repeated episode of depression. The intensity of depressive symptoms was not indicated by the stress impact of the experienced life events both in the onset (t=0.039 P>0.05) and the repeated episode of illness.
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