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[Catheters in patients with acute leukaemia]
Srpski Arhiv Za Celokupno Lekarstvo
|September 1, 1989
Summary
Central venous catheter complications are common in acute leukemia patients, with thrombosis and inflammation being most frequent. Preventive measures can reduce these risks during intensive therapy.
Area of Science:
- Hematology
- Vascular Access Devices
- Infectious Disease
Background:
- Central venous catheters (CVCs) are essential for intensive leukemia therapy.
- Complications associated with CVC use can significantly impact patient outcomes.
Purpose of the Study:
- To determine the types and frequency of complications during CVC use in adults with acute leukemia.
- To evaluate the efficacy of recanalization for thrombosed catheters.
Main Methods:
- A one-year prospective study involving 33 consecutive acute leukemia patients.
- Monitoring of 35 central venous catheters for complications during intensive therapy.
Main Results:
- A total of 30 complications were registered across 35 catheters.
- Complications included local inflammation (23%), thrombosis (partial 23%, complete 19%), catheter-related sepsis (10%), and early/miscellaneous complications (10-15%).
- Complete thrombosis was successfully treated with streptokinase and fresh frozen plasma.
Conclusions:
- Central venous catheter complications are frequent in acute leukemia patients undergoing intensive therapy.
- Preventive strategies, including aseptic techniques and modern catheter types, are crucial for reducing complication rates.
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