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Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Protein nanopatterns for improved immunodetection sensitivity
A Valsesia1, I Mannelli, P Colpo
1European Commission, Joint Research Centre, Institute for Health and Consumer Protection, 21020 Ispra (VA), Italy. andrea.valsesia@jrc.it
Analytical Chemistry
|August 20, 2008
Abstract:
In this work, we clearly demonstrate the capability of protein nanopatterns of improving the quality factors of immunosensing devices, such as lowering of the limit of detection and increase of sensitivity. This beneficial effect is obtained by the formation on the sensor's surface of bioadhesive domains of nanometric dimensions in a nonadhesive matrix by means of colloidal lithography.

