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Updated: Jul 2, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Exophytic intramedullary meningioma of the cervical spinal cord
D Sahni1, J S Harrop, I H Kalfas
1Department of Neurosurgery, Baylor College of Medicine, 1711 Old Spanish Trail, Houston, Texas 77054, USA. dds41@columbia.edu
Abstract:
Intramedullary spinal cord neoplasms are relatively uncommon. The most common intramedullary tumors are astrocytomas and ependymomas. Meningiomas can occur as an intradural tumor; however, they are typically in the extramedullary compartment. A 42-year-old male presented with progressive sensory loss in the upper extremities and lower extremity weakness. Pre-operative imaging suggested an intramedullary cervical lesion. To treat the progressive neurological abnormality, surgical resection was planned. At surgery, it was noted that the tumor originated in the cervical spinal cord and extended into the extramedullary region. Histology confirmed the lesion to be a meningioma. This meningioma variant has not previously been described. Spinal meningiomas may occur in locations other than intradural, extramedullary locations, and should be included in the differential diagnosis of intramedullary lesions. Intramedullary meningiomas can be successfully treated with surgery.
Insights
This study describes a rare case of an intramedullary spinal meningioma, a tumor typically found outside the spinal cord. This finding expands the understanding of spinal cord tumors and their surgical treatment.
Area of Science:
- Neurosurgery
- Neuropathology
- Oncology
Background:
- Intramedullary spinal cord neoplasms are uncommon, with astrocytomas and ependymomas being the most frequent.
- Meningiomas are typically intradural and extramedullary, rarely presenting within the spinal cord itself.
Observation:
- A 42-year-old male presented with progressive neurological deficits, including sensory loss and lower extremity weakness.
- Pre-operative imaging indicated an intramedullary cervical lesion.
- Surgical exploration revealed a tumor originating within the cervical spinal cord and extending extramedullaryly.
Findings:
- Histological examination confirmed the lesion as a meningioma.
- This represents a previously undescribed variant of spinal meningioma.
- The tumor demonstrated both intramedullary and extramedullary components.
Implications:
- Spinal meningiomas should be considered in the differential diagnosis of intramedullary spinal lesions.
- This case expands the known anatomical locations for spinal meningiomas.
- Surgical resection is a viable and successful treatment option for intramedullary meningiomas.
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