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Related Concept Videos

Dosage Interval and Administration Route: Determination Methods01:19

Dosage Interval and Administration Route: Determination Methods

A medication’s effectiveness largely depends on its appropriate dosage and the route of administration. Dosage ensures that a sufficient drug concentration is maintained in the bloodstream to elicit the desired therapeutic effect without causing toxicity. The route of administration affects the drug's bioavailability, rate of absorption, and onset of action, which are crucial for achieving optimal therapeutic outcomes. Drug dosage calculations are critical to tailoring therapy to individual...
Routes of Drug Administration: Parenteral01:25

Routes of Drug Administration: Parenteral

The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
One-Compartment Open Model for IV Bolus Administration: General Considerations01:19

One-Compartment Open Model for IV Bolus Administration: General Considerations

The one-compartment model is a pharmacokinetic tool that models the body as a single, uniform compartment, facilitating the understanding of drug distribution and elimination. This model is particularly beneficial for intravenous (IV) bolus administration, where the drug rapidly circulates throughout the body.
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant, half-life,...
One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...

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Intravenous therapy: preparation and administration of IV medicines.

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Infection control in IV therapy: a review of the chain of infection.

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Aseptic non-touch technique in intravenous therapy.

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Venepuncture practice and the 2008 Nursing and Midwifery Council Code.

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Peripheral vascular access devices: risk prevention and management.

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Related Experiment Video

Updated: Jul 2, 2026

Methods for Intravenous Self Administration in a Mouse Model
12:09

Methods for Intravenous Self Administration in a Mouse Model

Published on: December 8, 2012

Safe practice in intravenous medicines administration.

Irene Lavery1, Paula Ingram

  • 1Western General Hospital, Edinburgh. Irene.lavery@luht.scot.nhs.uk

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|August 21, 2008
PubMed
Summary

This guide details safe and effective intravenous (IV) medicine administration. It covers IV route benefits, risks, and essential good practice standards for healthcare professionals.

Area of Science:

  • Medicine
  • Pharmacology
  • Patient Safety

Background:

  • Intravenous (IV) drug administration is a common route for delivering medications.
  • Ensuring safe and effective IV administration is crucial for patient outcomes.
  • Understanding potential hazards and complications is vital for healthcare providers.

Purpose of the Study:

  • To provide a practical guide for safe and effective intravenous medicine injection.
  • To outline the benefits associated with the intravenous route of drug administration.
  • To detail potential hazards and complications of IV therapy and risk assessment.

Main Methods:

  • Review of current literature and clinical guidelines on intravenous drug administration.
  • Risk assessment framework for identifying and mitigating potential complications.

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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice
05:55

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice

Published on: October 3, 2011

Related Experiment Videos

Last Updated: Jul 2, 2026

Methods for Intravenous Self Administration in a Mouse Model
12:09

Methods for Intravenous Self Administration in a Mouse Model

Published on: December 8, 2012

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice
05:55

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice

Published on: October 3, 2011

  • Development of best practice standards for safe IV injection techniques.
  • Main Results:

    • The intravenous route offers rapid and efficient drug delivery.
    • Potential complications include infection, phlebitis, and extravasation.
    • Adherence to risk assessment and good practice standards minimizes adverse events.

    Conclusions:

    • Safe and effective IV medicine administration requires a thorough understanding of benefits and risks.
    • Implementation of established good practice standards is essential for patient safety.
    • Continuous education and vigilance are necessary to prevent and manage IV therapy complications.