Antimicrobial effect of oxidized cellulose salts

Area of Science:

• Materials Science
• Microbiology
• Biotechnology

Background:

• Oxidized cellulose is a modified biomaterial with potential applications.
• Antimicrobial properties of modified cellulose are of interest for various industries.

Purpose of the Study:

• To evaluate the antimicrobial efficacy of different forms of oxidized cellulose and its salts.
• To identify specific formulations with potent activity against a range of microorganisms.

Main Methods:

• Antimicrobial properties were tested using dilution and diffusion methods.
• A broad spectrum of bacterial and fungal strains were used for testing.
• Different forms of oxidized cellulose (linters, microspheres, textile) and salts (H, Zn, ZnNa, Ag) were evaluated.

Main Results:

• OKCEL Ag-L demonstrated antimicrobial activity against all tested bacteria and fungi (0.1-3.5% w/v).
• OKCEL ZnNa-M showed strong inhibition against specific bacteria and fungi (0.5-2.0% w/v).
• Textile forms (OKCEL Ag-T, OKCEL Zn-T, OKCEL H-T) exhibited high activity against key bacterial strains, with OKCEL Zn-T being particularly effective.

Conclusions:

• Oxidized cellulose and its silver and zinc-based salts possess significant antimicrobial properties.
• Formulation (linters, microspheres, textile) and specific salt type influence antimicrobial efficacy.
• These materials show promise for applications requiring microbial control.