TNF-alpha/IL-1/NF-kappaB transduction pathway in human cancer prostate

M Royuela1, G Rodríguez-Berriguete, B Fraile

  • 1Department of Cell Biology and Genetics, University of Alcalá, Alcalá de Henares, Madrid, Spain. mar.royuela@uah.es

Summary

Tumor necrosis factor-alpha (TNFalpha) and interleukin-1 (IL-1) signaling pathways promote prostate cancer proliferation. Inhibiting these pro-inflammatory cytokines may offer a novel therapeutic strategy for prostate cancer (PC).

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