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Related Experiment Video

Updated: Jul 2, 2026

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

Extra-1 acupressure for children undergoing anesthesia.

Shu-Ming Wang1, Sandra Escalera, Eric C Lin

  • 1Department of Anesthesiology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA. shu-ming.wang@yale.edu

Anesthesia and Analgesia
|August 21, 2008
PubMed
Summary

Acupressure at the Extra-1 (Yin-Tang) point effectively reduced preprocedural anxiety in children undergoing endoscopic procedures. However, it did not affect intraprocedural propofol requirements or Bispectral Index (BIS) values.

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Last Updated: Jul 2, 2026

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

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Published on: June 21, 2024

Area of Science:

  • Anesthesiology
  • Integrative Medicine
  • Pediatric Endoscopy

Background:

  • Acupuncture and related techniques are explored for perioperative anesthesia management.
  • The efficacy of acupressure at the Extra-1 (Yin-Tang) point for pediatric anxiety and anesthetic needs is investigated.

Purpose of the Study:

  • To determine if acupressure at the Extra-1 point reduces preprocedural anxiety in children.
  • To assess the impact of Extra-1 acupressure on intraprocedural propofol requirements during endoscopic procedures.

Main Methods:

  • Fifty-two children were randomized to receive acupressure at the Extra-1 point or a sham point.
  • Anxiety was measured pre-intervention and pre-operation; Bispectral Index (BIS) monitored sedation levels.
  • Propofol infusion was standardized to maintain BIS values between 40-60.

Main Results:

  • Children receiving Extra-1 acupressure showed reduced anxiety, while the sham group exhibited increased anxiety (P=0.012).
  • No significant differences in BIS values were observed between groups during the preprocedural period.
  • Total intraprocedural propofol requirements were similar between the Extra-1 and sham groups (P=0.52).

Conclusions:

  • Extra-1 acupoint acupressure effectively reduces preprocedural anxiety in pediatric patients undergoing endoscopy.
  • This acupressure intervention does not influence intraprocedural BIS values or propofol consumption.
  • Acupressure may serve as a non-pharmacological adjunct for managing anxiety in pediatric procedural settings.