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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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Apoptotic cell-mediated immunoregulation of dendritic cells does not require iC3b opsonization

Edward M Behrens1, Yue Ning, Nidal Muvarak

  • 1Laboratory of Dendritic Cell Biology, Division of Rheumatology, Joseph Stokes, Jr. Research Institute, Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA. behrens@email.chop.edu

Journal of Immunology (Baltimore, Md. : 1950)
|August 21, 2008
PubMed
Summary

Complement receptor 3 (CR3) engagement by apoptotic cells does not suppress dendritic cell (DC) immune responses. CR3 interaction is dispensable for the anti-inflammatory effects of apoptotic cells on DCs.

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