Related Experiment Video
Updated: Jul 2, 2026
05:32
Transient Middle Cerebral Artery Occlusion Model of Stroke
Published on: August 11, 2023
[Inferior temporal branch arterial occlusion--acute form]
Daniela Selaru1, Robertina Radocea, Horia Stanca
1Clinica de Oftalmologie, Spitalul Clinic De Urgenţă Militar Central, Bucureşti.
Oftalmologia (Bucharest, Romania : 1990)
|August 22, 2008
Summary
A 72-year-old smoker with complex health issues experienced acute Branch Retinal Artery Occlusion. A novel Nd:YAG laser photo-embolysis technique was successfully used as a Romanian first.
Area of Science:
- Ophthalmology
- Vascular Medicine
- Interventional Cardiology
Background:
- A 72-year-old female patient with a significant smoking history (50 years) presented with multiple comorbidities including coronary artery disease, heart failure, a hypercoagulable state, left carotid artery stenosis, and treated breast carcinoma.
- The patient was admitted to the Ophthalmology Clinic with a diagnosis of acute Left Eye Branch Retinal Artery Occlusion (temporal inferior type), occurring 10 days prior to admission.
Observation:
- The primary symptom was a superior altitudinal visual field deficit in the left eye.
- Notably, the patient's left eye visual acuity remained unaffected (20/20 best-corrected), attributed to the presence of two cilio-retinal arteries supplying the retina.
- A comprehensive ocular and systemic evaluation was conducted.
Findings:
- The occlusion involved the temporal inferior branch of the Central Retinal Artery.
- The decision was made to attempt trans-luminal photo-embolysis of the embolus using an Nd:YAG laser, given the timing since the onset of Branch Retinal Artery Occlusion.
Implications:
- This case highlights a successful application of trans-luminal photo-embolysis for Branch Retinal Artery Occlusion.
- The use of Nd:YAG laser for this indication represents a national premiere in Romania.
- The successful intervention in a patient with significant cardiovascular risk factors underscores the potential of this technique.
Related Concept Videos
01:10The Arch of Aorta
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
01:26Transient Ischemic Attack l: Introduction
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
01:26Arteries of the Head and Neck
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...