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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Anetodermic pilomatricoma.

Elemir M de Souza1, Andrelou F Ayres Vallarelli, Maria L Cintra

  • 1Dermatology Service, School of Medicine, State University of Campinas, São Paulo, Brazil.

Journal of Cutaneous Pathology
|August 22, 2008
PubMed
Summary

A pilomatricoma, a rare hair matrix tumor, can present with unusual skin changes like anetoderma. This case highlights the varied clinical and histological features of pilomatricoma in a young patient.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Pilomatricoma (calcifying epithelioma of Malherbe) is an uncommon benign skin tumor arising from hair matrix cells.
  • Clinically, it typically presents as a solitary, firm nodule, but overlying skin changes can alter its appearance.

Observation:

  • A rare case of pilomatricoma with associated anetoderma was observed on the lower extremity of a 12-year-old girl.
  • Histological examination revealed a thinned dermis with myxomatous changes and a deep tumoral mass.

Findings:

  • The pilomatricoma mass consisted of basaloid cells, shadow cells, and calcified areas.
  • Discrete inflammatory and foreign-body reactions were noted around the tumor.
  • Anetodermic changes were present despite the absence of clear triggering factors within the pilomatricoma.

Implications:

  • This case expands the understanding of pilomatricoma's variable clinical presentations.
  • It suggests that anetodermic changes can be associated with pilomatricoma, even without identifiable specific causes.
  • Highlights the importance of thorough histological evaluation for diagnosing pilomatricoma and associated conditions.