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Abstract:
Experimental and clinical data show the zone of hormonal stimulation of gastric juice secretion and that of parietal gastric hydrolysis to have well-defined borders coinciding with anatomical reference points, to be characterized by multidirectional gradient and to be a local mechanism regulating secretory and motor gastric activity. The condition of the lesser curvature ++muco-epithelial complex is one of the factors operable in development of gastroduodenal ulcer. It is hold that resection of hormone--contact zone of the stomach is a preserving, effective and available means of surgical management of gastroduodenal ulcer.