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Image guided IMRT dosimetry using anatomy specific MOSFET configurations.

Md Nurul Amin¹, Bern Norrlinger¹, Robert Heaton^1,2

¹Department of Radiation Physics, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.

Journal of Applied Clinical Medical Physics

|August 22, 2008

Summary

Multiple Metal-Oxide-Semiconductor Field-Effect Transistor (MOSFET) detectors offer a feasible method for quality assurance (QA) of Intensity Modulated Radiation Therapy (IMRT) plans. This dosimetry system provides accurate dose measurements, enhancing IMRT plan verification.

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Area of Science:

Medical Physics
Radiation Oncology
Dosimetry

Background:

Intensity Modulated Radiation Therapy (IMRT) requires rigorous quality assurance (QA) for accurate dose delivery.
Traditional dosimetry methods can be time-consuming and may not capture dose variations in complex treatment plans.
Metal-Oxide-Semiconductor Field-Effect Transistor (MOSFET) detectors offer potential for efficient and precise dose measurement.

Purpose of the Study:

To investigate the feasibility of using multiple MOSFET detectors for comprehensive IMRT plan QA.
To develop and evaluate anatomy-specific MOSFET configurations for a dedicated IMRT phantom.
To assess the accuracy and precision of MOSFET dosimetry compared to ion chamber measurements.

Main Methods:

Developed anatomy-specific configurations using 5 MOSFETs in a specialized IMRT phantom.

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Utilized kilovoltage cone beam computed tomography (kV CBCT) for precise detector and phantom positioning.

Compared MOSFET-measured doses with ion chamber measurements and treatment planning system (TPS) calculations.

Achieved 1 mm detector positioning precision using the X-Ray Volume Imaging (XVI) kV CBCT system.

Main Results:

Agreement between MOSFET and ion chamber measurements was within -0.26 +/- 0.88% (high dose) and 0.06 +/- 1.94% (low dose).
Agreement between MOSFET measurements and TPS calculations for head and neck and prostate IMRT plans was within 0.47 +/- 2.45%.
Simultaneous measurements at five points in high and low dose regions were performed efficiently.

Conclusions:

A multi-MOSFET system with anatomy-specific configurations and image guidance is effective for IMRT QA.
This method enhances the comprehensiveness and efficiency of IMRT plan quality assurance.
MOSFET dosimetry provides accurate and precise measurements, comparable to ion chambers, in IMRT dose verification.