Related Experiment Video
Updated: Jul 2, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
[Double-step distraction osteogenesis in the reconstruction of unilateral mandibular segmental defects after tumor
Jun Chen1, Fei-Yun Ping, Jun-Lie Yan
1Department of Oral and Maxillofacial Surgery, 2nd Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou 310009, China.
Objective:
To investigate the application of double-step distraction osteogenesis in the reconstruction of mandibular segmental defects after tumor resection.
Methods:
From January 2002 to December 2006, six cases of post-tumor unilateral mandibular segmental defects were reconstructed using distraction osteogenesis. The mandibular body was lengthened first, following by mandibular ramus distraction.
Results:
No infection or other complication was observed. The maximal distraction length reached 55 millimeter in the mandibular body, and 42 millimeter in the mandibular ramus. The average distraction length was 52 millimeter in the mandibular body, and 34 millimeter in the mandibular ramus. Both the aesthetic and functional result was excellent in all cases.
Conclusions:
Double-step distraction osteogenesis is effective and easily performed in the reconstruction of unilateral mandibular segmental defects with less morbidities and complications. There is no need for donor site. However, the treatment period is relatively long with three staged operations.
