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Related Concept Videos

Oscillations about an Equilibrium Position01:04

Oscillations about an Equilibrium Position

Stability is an important concept in oscillation. If an equilibrium point is stable, a slight disturbance of an object that is initially at the stable equilibrium point will cause the object to oscillate around that point. For an unstable equilibrium point, if the object is disturbed slightly, it will not return to the equilibrium point. There are three conditions for equilibrium points—stable, unstable, and half-stable. A half-stable equilibrium point is also unstable, but is named so because...
Damped Oscillations01:07

Damped Oscillations

In the real world, oscillations seldom follow true simple harmonic motion. A system that continues its motion indefinitely without losing its amplitude is termed undamped. However, friction of some sort usually dampens the motion, so it fades away or needs more force to continue. For example, a guitar string stops oscillating a few seconds after being plucked. Similarly, one must continually push a swing to keep a child swinging on a playground.
Although friction and other non-conservative...
Forced Oscillations01:06

Forced Oscillations

When an oscillator is forced with a periodic driving force, the motion may seem chaotic. The motions of such oscillators are known as transients. After the transients die out, the oscillator reaches a steady state, where the motion is periodic, and the displacement is determined.
Oscillations In An LC Circuit01:30

Oscillations In An LC Circuit

An idealized LC circuit of zero resistance can oscillate without any source of emf by shifting the energy stored in the circuit between the electric and magnetic fields. In such an LC circuit, if the capacitor contains a charge q before the switch is closed, then all the energy of the circuit is initially stored in the electric field of the capacitor. This energy is given by
Propagation of Action Potentials01:23

Propagation of Action Potentials

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Simplified Synchronous Machine Model01:30

Simplified Synchronous Machine Model

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Related Experiment Video

Updated: Jul 2, 2026

Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram
06:12

Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram

Published on: March 13, 2018

Applying saccade models to account for oscillations.

S Ramat1, R J Leigh, D S Zee

  • 1Dipartimento di Informatica e Sistemistica, Università degli Studi di Pavia, Pavia, Italy. stefano.ramat@unipv.it

Progress in Brain Research
|August 23, 2008
PubMed
Summary

Saccadic oscillations, rapid eye movements, can occur normally or indicate disease. A new model explains these oscillations via premotor circuit feedback, suggesting reduced omnipause neuron inhibition as a cause.

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Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function
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Last Updated: Jul 2, 2026

Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram
06:12

Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram

Published on: March 13, 2018

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function
05:44

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Published on: July 14, 2016

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Computational Biology

Background:

  • Saccadic oscillations are high-frequency eye movements (15-30 Hz) that can be transient in healthy individuals or indicative of neurological disease.
  • Pathological saccadic oscillations include flutter and opsoclonus, associated with specific medical conditions.

Purpose of the Study:

  • To review recent findings and hypotheses regarding the generation of saccadic oscillations.
  • To demonstrate how a mathematical model of the saccadic premotor circuitry can reproduce saccadic oscillations.

Main Methods:

  • Development of a mathematical model of the saccadic premotor circuit, incorporating brainstem burst neurons in the paramedian pontine reticular formation (PPRF).
  • Inclusion of the physiological phenomenon of post-inhibitory rebound (PIR) in model neurons.
  • Simulation of saccadic oscillations by manipulating positive feedback among excitatory and inhibitory burst neurons and reducing omnipause neuron inhibitory efficacy.

Main Results:

  • The model successfully reproduces saccadic oscillations due to positive feedback among excitatory and inhibitory burst neurons.
  • Reducing the inhibitory efficacy of omnipause neurons in the model leads to the generation of saccadic oscillations.

Conclusions:

  • Positive feedback within the saccadic premotor circuit is a key mechanism for generating saccadic oscillations.
  • Altered inhibition by omnipause neurons may underlie pathological saccadic oscillations, providing insights into their neurological basis.