A novel needle-type sampling device for flexible ultrathin bronchoscopy

Area of Science:

• Pulmonology
• Oncology
• Medical Devices

Background:

• Diagnosing peripheral lung cancer is challenging due to limitations of standard bronchoscopes.
• Existing sampling devices for ultrathin bronchoscopes have inadequate diagnostic yield, especially for lesions not visible in the bronchial lumen.

Purpose of the Study:

• To develop and evaluate a novel needle-type sampling device for transbronchial cytology using flexible ultrathin bronchoscopes.
• To assess the diagnostic yield and feasibility of the new device for peripheral pulmonary lesions.

Main Methods:

• A novel needle-type sampling device was developed using a dental H-file, housing sheath, and a specialized handle.
• Ten patients with peripheral pulmonary lesions underwent diagnostic procedures using flexible ultrathin bronchoscopes.
• Virtual bronchoscopy and a novel bronchial route labeling system guided bronchoscope insertion.
• Sampling was performed with the novel needle prior to forceps and brush use under fluoroscopy.

Main Results:

• The novel needle sampling device was successfully used in all ten patients.
• Sufficient specimen amounts for cytology were obtained in every case.
• The procedure was minimally invasive and facilitated accurate diagnosis.

Conclusions:

• The novel needle sampling system integrated with flexible ultrathin bronchoscopes offers a promising approach for accurate and minimally invasive diagnosis of peripheral pulmonary lesions.
• This device may enhance diagnostic capabilities for difficult-to-reach lung abnormalities.