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Updated: Jul 2, 2026
05:31
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
[Percutaneous aortic aortic valve replacement: myth or reality?]
1Universidade Luterana do Brasil (ULBRA), Porto Alegre, RS, Brasil.
Summary
Transcatheter aortic valve implantation offers a less invasive option for high-risk patients with severe aortic stenosis. This review explores the development and clinical application of this novel treatment, highlighting its potential impact.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Surgery
Context:
- Conventional aortic valve replacement (AVR) with extracorporeal circulation is standard for calcific aortic stenosis.
- Elderly patients with comorbidities, reoperations, or severe left ventricular dysfunction face high surgical risks with traditional AVR.
- Percutaneous techniques have emerged as a significant advancement in treating aortic stenosis.
Purpose:
- To review the literature on percutaneous aortic valve implantation (PAVI).
- To trace the development from experimental stages to clinical application of PAVI.
- To assess PAVI as a treatment for patients with severe aortic stenosis and high surgical risk.
Summary:
- Surgical aortic valve replacement is the gold standard for aortic stenosis but carries high risks for certain patient groups.
- Percutaneous aortic valve implantation has been developed as an alternative for high-risk surgical candidates.
- This review analyzes the literature on the evolution and clinical use of PAVI in patients with severe aortic stenosis.
Impact:
- PAVI provides a less invasive therapeutic option for high-risk patients with severe aortic stenosis.
- Cardiovascular surgeons play a crucial role in the development and application of percutaneous aortic valve procedures.
- The adoption of PAVI signifies a paradigm shift in managing complex aortic valve disease.
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