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Updated: Jul 2, 2026

Assembly, Tuning and Use of an Apertureless Near Field Infrared Microscope for Protein Imaging
Published on: November 25, 2009
[Development of aperture probe near-field Raman spectroscopy and microscopy]
Yang Jiang1, Bin Ren, Zhong-Qun Tian
1State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China. yjiang@xmu.edu.cn
Abstract:
The appearance of near-field Raman spectroscopy that is based on aperture probe scanning near-field optical microscopy makes the resolution of Raman spectroscopy beyond the optical diffraction limitation. It provided a powerful tool to probe chemical information of sample on subwavelength scale. The present article illustrates the influence of probe character on near field Raman spectroscopy. Furthermore, the development over ten years in chemical resolution imaging on nanoscale, special properties of liquid-liquid interface, exploring SERS mechanism and observing hotspots beneath subwavelength scale etc. were introduced in detail.
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