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Low-risk gestational trophoblastic neoplasia: evaluating the need for initial inpatient treatment during low-dose
Lucy D Carter1, Barry W Hancock, Janet E Everard
1Trophoblastic Tumour Centre, Weston Park Hospital, Sheffield, UK.
Objective:
To evaluate the need for initial inpatient treatment for patients being treated with low-dose intramuscular methotrexate for low-risk gestational trophoblastic neoplasia (GTN).
Study Design:
Clinical notes of all patients treated with low-dose intramuscular methotrexate for low-risk GTN were analyzed and side effects noted.
Results:
There were no episodes of increased uterine bleeding requiring extra medical intervention. There were 7 cases of chest pain; none required a change from methotrexate chemotherapy.
Conclusion:
Patients being treated with low-dose intramuscular methotrexate for low-risk GTN do not need to be treated routinely in the hospital for their first treatment cycle.