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Updated: Jul 2, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
Sensitive and selective fluorescence determination of trace hydrazine in aqueous solution utilizing
Xiaotong Chen1, Yu Xiang, Zifan Li
1Department of Chemistry, Tsinghua University, Beijing 100084, PR China.
Abstract:
A facile fluorescent method for the determination of hydrazine in aqueous solution with excellent sensitivity was developed. 5-chlorosalicylaldehyde (CS), a readily commercially available compound, was applied as the derivatization reagent in this work. Under the addition of CS to hydrazine aqueous solution (ethanol/water/acetic acid=30/66/4), an intense fluorescence enhancement was observed at 570 nm with a large stokes shift of approximately 170 nm. Upon the optimal condition, the fluorescence intensity linearly increased with the concentration of hydrazine in the range of 0.2 and 9.3 microM with a correlation coefficient of R2=0.9995 (n=10) and a detection limit of 0.08 microM. The R.S.D. was 2.0% (n=5). Determination of hydrazine in river and drinking water samples was successfully performed. Hydrazine vapor sensing by the proposed method was also reported.
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