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Related Experiment Video

Updated: Jul 2, 2026

Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

Multimodal pain management and arthrofibrosis.

Carlos Lavernia1, Diego Cardona, Mark D Rossi

  • 1Arthritis Surgery Research Foundation, Inc., Miami, Florida, USA.

The Journal of Arthroplasty
|September 9, 2008
PubMed
Summary

Implementing a multimodal pain management protocol significantly reduced the need for manipulation after total knee arthroplasty (TKA). This approach offers improved outcomes for patients undergoing TKA surgery.

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

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Area of Science:

  • Orthopedic Surgery
  • Pain Management
  • Arthroplasty Research

Background:

  • Post-arthroplasty pain and limited range of motion are significant concerns for orthopedic surgeons.
  • Arthrofibrosis, a complication of total knee arthroplasty (TKA), can lead to persistent joint pain and stiffness.
  • Manipulation under anesthesia is a common intervention to improve joint mobility and reduce pain post-TKA.

Purpose of the Study:

  • To evaluate the impact of a multimodal pain management protocol on the incidence of arthrofibrosis in primary total knee arthroplasty (TKA).

Main Methods:

  • A retrospective cohort study involving 1136 patients undergoing primary TKA.
  • Patients were divided into two groups: Group A (778 procedures) received traditional pain control, and Group B (358 procedures) received a multimodal pain management protocol.

Related Experiment Videos

Last Updated: Jul 2, 2026

Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

  • The incidence of manipulation under anesthesia was compared between the two groups.

    • Main Results:

    • The incidence of manipulation was 4.75% (37/778) in the traditional pain control group (Group A).
    • The multimodal pain management group (Group B) showed a significantly lower incidence of manipulation at 2.24% (8/357).

    Conclusions:

    • A multimodal pain management protocol is associated with a reduced need for manipulation after primary total knee arthroplasty.
    • Orthopedic surgeons should consider adopting multimodal pain management strategies to improve patient outcomes following TKA.