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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...

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Related Experiment Video

Updated: Jul 2, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
05:31

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

Regional infusion-radioembolization.

Gregory J Dubel1, Gregory M Soares

  • 1Department of Diagnostic Imaging, Warren Alpert School of Medicine Brown University, Division of Interventional Radiology, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. gdubel@lifespan.org

Surgical Oncology Clinics of North America
|August 30, 2008
PubMed
Summary
This summary is machine-generated.

Selective internal radiation therapy, also known as radioembolization, is an effective treatment for liver tumors like hepatocellular carcinoma (HCC) and metastatic colorectal carcinoma (MCRC). This minimally invasive procedure shows high response rates and improved survival with uncommon complications when performed meticulously.

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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Area of Science:

  • Oncology
  • Radiology
  • Interventional Radiology

Background:

  • Selective internal radiation therapy (SIRT), or radioembolization, delivers radioactive microspheres intra-arterially to tumors.
  • This method aims to maximize tumor radiation dose while minimizing exposure to surrounding organs.

Purpose of the Study:

  • To review the established and emerging applications of radioembolization.
  • To summarize treatment outcomes, response rates, and potential complications.
  • To discuss the importance of patient selection and technique in radioembolization therapy.

Main Methods:

  • Review of global patient treatment data (>8000 patients).
  • Analysis of response rates using FDG-PET imaging.
  • Evaluation of complication profiles and survival data.

Main Results:

  • High response rates (80%-90%) observed via FDG-PET.
  • Significant improvement in median survival for HCC and MCRC patients compared to historical controls.
  • Complications are infrequent, with malaise being most common; significant complications occur in up to 10%.

Conclusions:

  • Radioembolization is a well-established treatment for HCC and MCRC with proven survival benefits.
  • Meticulous technique and careful patient selection are crucial for minimizing complications.
  • Further research is needed to define its role alongside modern chemotherapy and other liver-directed treatments.