Related Experiment Video

Updated: Jul 2, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

[Quality of life in children with epilepsy: a review]

C Soria1, C Bulteau, S El Sabbagh

  • 1CNRS UMR 8189, laboratoire de psychologie et de neurosciences cognitives, institut de psychologie, université Paris Descartes, Boulogne-Billancourt, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|August 30, 2008
PubMed

Insights

Assessing health-related quality of life (HRQOL) in children with epilepsy is complex, involving child and family factors. This review examines HRQOL assessment methods, highlighting a French study

Area of Science:

  • Pediatric Neurology
  • Quality of Life Research
  • Psychometrics

Context:

  • Epilepsy significantly impacts children's lives, affecting behavior, cognition, and social interactions.
  • Assessing health-related quality of life (HRQOL) in pediatric epilepsy is crucial but challenging due to its multidimensional nature.
  • Existing HRQOL measures often rely on parental reports, with growing interest in child-centered perspectives.

Purpose:

  • To review existing methodologies for assessing HRQOL in children with epilepsy.
  • To explore the evolution of HRQOL assessment tools, including those incorporating the child's viewpoint.
  • To present preliminary findings from a large-scale French study on pediatric epilepsy HRQOL.

Summary:

  • Health-related quality of life (HRQOL) in pediatric epilepsy encompasses general well-being and epilepsy-specific concerns.
  • Current assessment predominantly uses parental reports, but child-reported outcomes are increasingly important.
  • HRQOL data informs clinical trials, treatment evaluations (especially surgical), and comprehensive patient care.

Impact:

  • Provides a comprehensive overview of HRQOL assessment tools for pediatric epilepsy.
  • Highlights the need for diverse perspectives (child, parent, clinician) in HRQOL evaluation.
  • Contributes preliminary data from a French cohort, addressing a gap in large-scale studies.

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Sampling Cerebrospinal Fluid and Blood from Lateral Tail Vein in Rats During EEG Recordings10:46

Sampling Cerebrospinal Fluid and Blood from Lateral Tail Vein in Rats During EEG Recordings

Published on: September 1, 2023

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...